Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.58 |
| ▸ | RARB | P10826 | 3/20 | 0.57 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.56 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | LSS | P48449 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27974031 | 0.90 | LTA4H (0.66) | LTA4HNR5A1CHRNA7CYP2C19TP53 | |
| SCHEMBL15923575 | 0.90 | LTA4H (0.66) | LTA4HNR5A1CHRNA7CYP2C19TP53 | |
| SCHEMBL1533788 | 0.90 | LTA4H (0.70) | LTA4HRARBNR5A1CHRNA7LSS | |
| SCHEMBL9154156 | 0.90 | LTA4H (0.70) | LTA4HRARBNR5A1CHRNA7LSS | |
| SCHEMBL9150960 | 0.90 | LTA4H (0.70) | LTA4HRARBNR5A1CHRNA7LSS | |
| SCHEMBL8972519 | 0.90 | LTA4H (0.70) | LTA4HRARBNR5A1CHRNA7LSS | |
| SCHEMBL9500464 | 0.90 | LTA4H (0.70) | LTA4HRARBNR5A1CHRNA7LSS | |
| SCHEMBL9154968 | 0.90 | LTA4H (0.70) | LTA4HRARBNR5A1CHRNA7LSS | |
| SCHEMBL17850556 | 0.90 | LTA4H (0.70) | LTA4HRARBNR5A1CHRNA7LSS | |
| SCHEMBL9155701 | 0.90 | LTA4H (0.70) | LTA4HRARBNR5A1CHRNA7LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376294-B1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| US-5370821-A | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5269965-A | Optically active compounds, liquid crystal compositions comprising said compounds and liquid crystal optical modulators using said compositions | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0376294-A1 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1990-07-04 | — | — | EP | disclosed |