Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 9/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16367683 | 1.00 | TSHR (0.40) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL8972346 | 0.85 | LMNA (0.37) | TSHRACACBMAPTRAB9AMMP1 | |
| SCHEMBL8972157 | 0.84 | MGAM (0.46) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL1369013 | 0.82 | CYP2D6 (0.53) | CYP2D6CA12CA7CA9CA14 | |
| SCHEMBL1369011 | 0.82 | CYP2D6 (0.53) | CYP2D6CA12CA7CA9CA14 | |
| SCHEMBL8971704 | 0.82 | CYP2D6 (0.53) | CYP2D6CA12CA7CA14 | |
| SCHEMBL2385474 | 0.82 | CYP2D6 (0.53) | CYP2D6CA12CA7CA9CA14 | |
| SCHEMBL29689264 | 0.82 | CYP2D6 (0.53) | CYP2D6CA12CA7CA9CA14 | |
| SCHEMBL1144274 | 0.82 | MGAM (0.42) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL754155 | 0.82 | ACACB (0.36) | ACACBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523414-A | PRODUCING MALEIMIDE BY HEATING MALEAMIC ACID ESTER IN INERT ORGANIC SOLVENT IN PRESENCE OF MONOALKYL SULFATE CATALYST | NIPPON SHOKUBAI CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| US-5518903-A | HYDROLYSIS OF ESTER | CHISSO CORPORATION (JP) | 1996-05-21 | — | — | US | disclosed |
| EP-0672650-A1 | PROCESSES FOR PRODUCING MALEAMIC ACID, ESTER THEREOF AND MALEIMIDE | NIPPON SHOKUBAI CO., LTD. (JP) | 1995-09-20 | — | — | EP | disclosed |