Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972299 | 1.00 | HTR2A (0.31) | HTR2AHTR2CHTR2B | |
| SCHEMBL8972294 | 1.00 | HTR2A (0.31) | HTR2AHTR2CHTR2B | |
| SCHEMBL8971544 | 0.88 | SLC6A2 (0.30) | — | |
| SCHEMBL8971556 | 0.88 | SLC6A2 (0.30) | — | |
| SCHEMBL8971534 | 0.88 | SLC6A2 (0.30) | — | |
| SCHEMBL13614939 | 0.86 | — | — | |
| SCHEMBL24462198 | 0.86 | — | — | |
| SCHEMBL10432665 | 0.85 | HTR2A (0.31) | HTR2AHTR2CHTR2B | |
| SCHEMBL10432666 | 0.85 | HTR2A (0.31) | HTR2AHTR2CHTR2B | |
| SCHEMBL8034756 | 0.84 | USP5 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433836-B1 | Halophenyl substituted dioxanes | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5322638-A | Halophenyl substituted dioxanes | HOFFMANN-LA ROCHE INC. (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0433836-A2 | Halophenyl substituted dioxanes | F. HOFFMANN-LA ROCHE AG (CH) | 1991-06-26 | — | — | EP | disclosed |