SCHEMBL8034756

SCHEMBL8034756

C=C[C@H]1CC[C@H]([C@H]2CO[C@H]([C@H]3CC[C@H](c4ccc(F)c(F)c4)CC3)OC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP5 P45974 2/20 0.32
HDAC6 Q9UBN7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8034760 1.00 USP5 (0.32) USP5HDAC6
SCHEMBL9135264 1.00 USP5 (0.32) USP5HDAC6
SCHEMBL8972410 0.91 USP5 (0.33) USP5HDAC6
SCHEMBL8972415 0.91 USP5 (0.33) USP5HDAC6
SCHEMBL8972418 0.91 USP5 (0.33) USP5HDAC6
SCHEMBL2847049 0.88 USP5 (0.34) USP5HDAC6
SCHEMBL6453970 0.88 USP5 (0.34) USP5HDAC6
SCHEMBL8771448 0.88 USP5 (0.34) USP5HDAC6
SCHEMBL12975888 0.87 USP5 (0.34) USP5HDAC6
SCHEMBL12975983 0.87 USP5 (0.34) USP5HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0497176-B1 Four rings compounds and liquid crystal mixtures containing them MERCK PATENT GMBH (DE) 2000-04-05 EP disclosed
US-5478497-A For electro-optical purposes HOFFMANN-LA ROCHE INC. (US) 1995-12-26 US disclosed