SCHEMBL8972334

SCHEMBL8972334

Cc1cccc(C(=O)O)c1-c1ccc(CBr)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.50
FABP4 P15090 1/20 0.49
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
HSD17B10 Q99714 2/20 0.46
DHODH Q02127 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C9 P11712 2/20 0.41
KMT2A Q03164 2/20 0.41
FFAR1 O14842 3/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
POLB P06746 1/20 0.40
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5937096 0.86 MYC (0.51) MYCFABP4KDM4EALDH1A1HPGD
SCHEMBL4986456 0.82 MYC (0.58) MYCFABP4KDM4EALDH1A1HPGD
SCHEMBL4363981 0.81 FABP4 (0.68) MYCFABP4KDM4EALDH1A1HPGD
Hydrochloric Acid SCHEMBL7605502 0.80 FABP4 (0.66) MYCFABP4KDM4EALDH1A1HPGD
SCHEMBL6804369 0.79 MYC (0.54) MYCFABP4KDM4EALDH1A1HPGD
Hydrochloric Acid SCHEMBL7907584 0.78 MYC (0.53) MYCFABP4KDM4EALDH1A1HPGD
SCHEMBL30481735 0.77 MYC (0.70) MYCFABP4KDM4EALDH1A1HPGD
SCHEMBL70391 0.77 MYC (0.70) MYCFABP4KDM4EALDH1A1HPGD
SCHEMBL6797502 0.76 MYC (0.51) MYCFABP4KDM4EALDH1A1HPGD
SCHEMBL4785732 0.76 MYC (0.51) MYCFABP4KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5506238-A HYPOTENSIVE AGENT EISAI CO., LTD. (JP) 1996-04-09 US disclosed