Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972418 | 1.00 | USP5 (0.33) | USP5HDAC6SCD5HTR2AHTR2C | |
| SCHEMBL8972410 | 1.00 | USP5 (0.33) | USP5HDAC6SCD5HTR2AHTR2C | |
| SCHEMBL9135264 | 0.91 | USP5 (0.32) | USP5HDAC6 | |
| SCHEMBL8034760 | 0.91 | USP5 (0.32) | USP5HDAC6 | |
| SCHEMBL8034756 | 0.91 | USP5 (0.32) | USP5HDAC6 | |
| SCHEMBL12975977 | 0.87 | USP5 (0.32) | USP5HDAC6SCD5 | |
| SCHEMBL8433761 | 0.85 | CYP11B1 (0.34) | — | |
| SCHEMBL8433759 | 0.85 | CYP11B1 (0.34) | — | |
| SCHEMBL8433763 | 0.85 | CYP11B1 (0.34) | — | |
| SCHEMBL8433760 | 0.85 | CYP11B1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433836-B1 | Halophenyl substituted dioxanes | HOFFMANN LA ROCHE (CH) | 1996-03-27 | — | — | EP | disclosed |
| US-5322638-A | Halophenyl substituted dioxanes | HOFFMANN-LA ROCHE INC. (US) | 1994-06-21 | — | — | US | disclosed |
| EP-0433836-A2 | Halophenyl substituted dioxanes | F. HOFFMANN-LA ROCHE AG (CH) | 1991-06-26 | — | — | EP | disclosed |