Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 5/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 4/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8972538 | 0.95 | ALDH1A1 (0.42) | ALDH1A1TLR2BACE1PLA2G2CCTSS | |
| SCHEMBL8971543 | 0.91 | ALDH1A1 (0.43) | ALDH1A1BACE1PLA2G2CCTSSBIRC2 | |
| SCHEMBL14269804 | 0.87 | NPY4R (0.43) | BACE1CTSD | |
| SCHEMBL9132373 | 0.87 | NPY4R (0.43) | BACE1CTSD | |
| SCHEMBL9132164 | 0.87 | NPY4R (0.43) | BACE1CTSD | |
| SCHEMBL8972038 | 0.87 | ALDH1A1 (0.44) | ALDH1A1BACE1PLA2G2CCTSSBIRC2 | |
| SCHEMBL9129549 | 0.77 | NPY4R (0.48) | — | |
| SCHEMBL21387168 | 0.76 | ALDH1A1 (0.50) | ALDH1A1BACE1CTSSBIRC2CTSK | |
| SCHEMBL8972090 | 0.76 | BIRC2 (0.43) | BACE1CTSSBIRC2CTSKREN | |
| SCHEMBL23133171 | 0.76 | BIRC2 (0.53) | ALDH1A1TLR2BIRC2SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543310-B1 | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LTD (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5395824-A | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LIMITED (JP) | 1995-03-07 | — | — | US | disclosed |