Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.61 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.60 |
| ▸ | REN | P00797 | 1/20 | 0.57 |
| ▸ | CPA1 | P15085 | 1/20 | 0.56 |
| ▸ | CPB1 | P15086 | 1/20 | 0.56 |
| ▸ | CPA2 | P48052 | 1/20 | 0.56 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12563719 | 1.00 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL23616326 | 0.91 | ALDH1A1 (0.66) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL27488362 | 0.91 | ALDH1A1 (0.68) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL3734223 | 0.91 | ALDH1A1 (0.68) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL15692334 | 0.88 | MME (0.65) | ALDH1A1CPA1CPB1CPA2CPA4 | |
| SCHEMBL30777486 | 0.88 | MME (0.65) | ALDH1A1CPA1CPB1CPA2CPA4 | |
| SCHEMBL1879654 | 0.88 | ATM (0.68) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL803579 | 0.88 | ATM (0.68) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL1884230 | 0.88 | ATM (0.68) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL15290564 | 0.88 | PSMB5 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543310-B1 | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LTD (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5395824-A | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LIMITED (JP) | 1995-03-07 | — | — | US | disclosed |