Phosphoric Acid

Phosphoric Acid

SCHEMBL8972909

CCCCCCCCCCCC(=O)NC(CO)CCCCCC.O=P(O)(O)O

nearest known ligand 0.59

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 2/20 0.59
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
DNM1 Q05193 1/20 0.55
PLA2G10 O15496 2/20 0.54
FAAH O00519 2/20 0.53
MAPK1 P28482 1/20 0.53
PLA2G4A P47712 3/20 0.52
CERT1 Q9Y5P4 3/20 0.51
PLA2G1B P04054 1/20 0.48
PLA2G2A P14555 1/20 0.48
LPAR3 Q9UBY5 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21428309 0.94 PLA2G2C (0.66) PLA2G2CMEN1KMT2ADNM1PLA2G10
SCHEMBL21428136 0.94 PLA2G2C (0.66) PLA2G2CMEN1KMT2ADNM1PLA2G10
SCHEMBL13018990 0.94 PLA2G2C (0.66) PLA2G2CMEN1KMT2ADNM1PLA2G10
SCHEMBL14627191 0.94 PLA2G2C (0.66) PLA2G2CMEN1KMT2ADNM1PLA2G10
SCHEMBL8733160 0.94 PLA2G2C (0.66) PLA2G2CMEN1KMT2ADNM1PLA2G10
SCHEMBL24767613 0.94 PLA2G2C (0.66) PLA2G2CMEN1KMT2ADNM1PLA2G10
SCHEMBL22911002 0.94 PLA2G2C (0.66) PLA2G2CMEN1KMT2ADNM1PLA2G10
SCHEMBL7618660 0.90 PLA2G2C (0.71) PLA2G2CMEN1KMT2ADNM1PLA2G10
SCHEMBL7618442 0.90 PLA2G2C (0.71) PLA2G2CMEN1KMT2ADNM1PLA2G10
SCHEMBL7621535 0.90 PLA2G2C (0.71) PLA2G2CMEN1KMT2ADNM1PLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0701561-A1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 LABORATORIOS MENARINI S.A. (ES) 1996-03-20 EP claimed
WO-1994028004-A1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 LABORATORIOS MENARINI S.A. (ES) 1994-12-08 WO claimed
EP-0701561-A1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 LABORATORIOS MENARINI S.A. (ES) 1996-03-20 EP disclosed
WO-1994028004-A1 DESOXYAZAPHOSPHOLIPID DERIVATIVES HAVING INHIBITING ACTIVITY ON PHOSPHOLIPASE A2 LABORATORIOS MENARINI S.A. (ES) 1994-12-08 WO disclosed