SCHEMBL8972999

SCHEMBL8972999

CCCCCCCCCC(=O)N1CCNCC1

nearest known ligand 0.69

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 10/20 0.69
GNAI1 P63096 10/20 0.69
GNAO1 P09471 9/20 0.69
L3MBTL1 Q9Y468 2/20 0.67
MEN1 O00255 1/20 0.65
KMT2A Q03164 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
NAAA Q02083 2/20 0.54
FAAH O00519 1/20 0.54
POLB P06746 1/20 0.46
ITGB3 P05106 1/20 0.45
ITGA2B P08514 1/20 0.45
ATM Q13315 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9120685 1.00 GNAI3 (0.69) GNAI3GNAI1GNAO1L3MBTL1MEN1
SCHEMBL6536788 1.00 GNAI3 (0.69) GNAI3GNAI1GNAO1L3MBTL1MEN1
SCHEMBL9658815 1.00 GNAI3 (0.69) GNAI3GNAI1GNAO1L3MBTL1MEN1
SCHEMBL18651303 1.00 GNAI3 (0.69) GNAI3GNAI1GNAO1L3MBTL1MEN1
SCHEMBL6488462 1.00 GNAI3 (0.69) GNAI3GNAI1GNAO1L3MBTL1MEN1
SCHEMBL3601270 1.00 GNAI3 (0.69) GNAI3GNAI1GNAO1L3MBTL1MEN1
SCHEMBL23533349 1.00 GNAI3 (0.69) GNAI3GNAI1GNAO1L3MBTL1MEN1
SCHEMBL8973027 1.00 GNAI3 (0.69) GNAI3GNAI1GNAO1L3MBTL1MEN1
SCHEMBL8973060 1.00 GNAI3 (0.69) GNAI3GNAI1GNAO1L3MBTL1MEN1
SCHEMBL9415674 1.00 GNAI3 (0.69) GNAI3GNAI1GNAO1L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268222-B1 Penetration enhancers for transdermal delivery of systemic agents RES TRIANGLE PHARM LTD (US) 1996-03-27 EP claimed
US-4917896-A PIPERAZINE, MORPHOLINE OR THIOMORPHOLINE DERIVATIVE NELSON RESEARCH & DEVELOPMENT CO. (US) 1990-04-17 US claimed
EP-0268222-A2 Penetration enhancers for transdermal delivery of systemic agents RESEARCH TRIANGLE PHARMACEUTICALS LTD. (US) 1988-05-25 EP claimed
WO-2025226833-A1 LIVER RECEPTOR HOMOLOG-1 (LRH-1) AGONIST ISOSTERES AND USES EMORY UNIVERSITY (US) 2025-10-30 WO disclosed
EP-0268222-B1 Penetration enhancers for transdermal delivery of systemic agents RES TRIANGLE PHARM LTD (US) 1996-03-27 EP disclosed
US-4917896-A PIPERAZINE, MORPHOLINE OR THIOMORPHOLINE DERIVATIVE NELSON RESEARCH & DEVELOPMENT CO. (US) 1990-04-17 US disclosed
EP-0268222-A2 Penetration enhancers for transdermal delivery of systemic agents RESEARCH TRIANGLE PHARMACEUTICALS LTD. (US) 1988-05-25 EP disclosed