Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9784840 | 0.99 | NAMPT (0.42) | NAMPTLMNAMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9784907 | 0.99 | NAMPT (0.42) | NAMPTLMNAMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9784843 | 0.99 | NAMPT (0.42) | NAMPTLMNAMEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9784897 | 0.99 | NAMPT (0.42) | NAMPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9784862 | 0.93 | LMNA (0.42) | LMNAMEN1KMT2ASMN1; SMN2BCHE | |
| SCHEMBL9784867 | 0.93 | LMNA (0.42) | LMNAMEN1KMT2ASMN1; SMN2BCHE | |
| Hydrochloric Acid SCHEMBL9784905 | 0.92 | LMNA (0.42) | LMNAMEN1KMT2ASMN1; SMN2BCHE | |
| Hydrochloric Acid SCHEMBL9784908 | 0.92 | LMNA (0.42) | LMNAMEN1KMT2ASMN1; SMN2BCHE | |
| SCHEMBL9504359 | 0.92 | LMNA (0.46) | LMNAMEN1KMT2ASMN1; SMN2BCHE | |
| Hydrochloric Acid SCHEMBL9784927 | 0.91 | LMNA (0.45) | LMNAMEN1KMT2ASMN1; SMN2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633780-B1 | USE OF PHENOTHIAZINE DERIVATIVES FOR TREATING ISCHAEMIA AND/OR HYPOXIA | RHONE POULENC RORER SA (FR) | 1996-06-05 | — | — | EP | claimed |
| US-5502049-A | AMINOALKYL AND AMIDE DERIVATIVES | RHONE-POULENC RORER S.A. (FR) | 1996-03-26 | — | — | US | claimed |