Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049868 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL4006166 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL1365242 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL11849992 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL16719251 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL1115015 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL1365853 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL1285241 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL454130 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1L3MBTL1KMT2A | |
| SCHEMBL31734806 | 1.00 | TSHR (0.67) | TSHRLMNAALDH1A1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250361250-A1 | FLUORINE-CONTAINING SILANE COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2025-11-27 | — | — | US | disclosed |
| WO-2024172034-A1 | FLUORINE-CONTAINING SILANE COMPOUND | ダイキン工業株式会社 | 2024-08-22 | — | — | WO | disclosed |
| US-20240216513-A1 | FATTY ACID-BIFUNCTIONAL DEGRADER CONJUGATES AND THEIR METHODS OF USE | NOVARTIS AG (CH) | 2024-07-04 | — | — | US | disclosed |
| US-20240216513-A1 | FATTY ACID-BIFUNCTIONAL DEGRADER CONJUGATES AND THEIR METHODS OF USE | NOVARTIS AG (CH) | 2024-07-04 | — | — | US | disclosed |
| US-20240216513-A1 | FATTY ACID-BIFUNCTIONAL DEGRADER CONJUGATES AND THEIR METHODS OF USE | NOVARTIS AG (CH) | 2024-07-04 | — | — | US | disclosed |
| EP-4304655-A1 | FATTY ACID-BIFUNCTIONAL DEGRADER CONJUGATES AND THEIR METHODS OF USE | Novartis AG (CH) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022189859-A1 | FATTY ACID-BIFUNCTIONAL DEGRADER CONJUGATES AND THEIR METHODS OF USE | NOVARTIS AG (CH) | 2022-09-15 | — | — | WO | disclosed |
| US-9287114-B2 | Method of modifying surfaces | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2016-03-15 | — | — | US | disclosed |
| US-20140203414-A1 | Method Of Modifying Surfaces | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2014-07-24 | — | — | US | disclosed |
| EP-2748352-A1 | METHOD OF MODIFYING SURFACES | University Court of The University of St Andrews (GB) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013030516-A1 | METHOD OF MODIFYING SURFACES | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2013-03-07 | — | — | WO | disclosed |
| EP-0485479-B1 | PERFLUORO-T-BUTYL-CONTAINING COMPOUNDS FOR USE IN FLUORINE-19 NMR AND/OR MRI | UNIV JOHNS HOPKINS (US) | 1996-04-03 | — | — | EP | disclosed |
| US-5397563-A | Perfluoro-t-butyl-containing steroids for use in fluorine-19 NMR and/or MRI | THE JOHNS HOPKINS UNIVERSITY (US) | 1995-03-14 | — | — | US | disclosed |
| US-5324504-A | Nine magnetically equivalent fluorine nuclei generate a single intense resonance for detection | THE JOHNS HOPKINS UNIVERSITY (US) | 1994-06-28 | — | — | US | disclosed |
| US-5234680-A | Generates single, intense resonance for easy detection in imaging or spectroscopy | JOHNS HOPKINS UNIV. (US) | 1993-08-10 | — | — | US | disclosed |
| US-5116599-A | Imaging compounds for medical diagnosis | JOHNS HOPKINS UNIV. (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0485479-A1 | PERFLUORO-T-BUTYL-CONTAINING COMPOUNDS FOR USE IN FLUORINE-19 NMR AND/OR MRI. | UNIV JOHNS HOPKINS (US) | 1992-05-20 | — | — | EP | disclosed |
| WO-1991001759-A1 | PERFLUORO-T-BUTYL-CONTAINING COMPOUNDS FOR USE IN FLUORINE-19 NMR AND/OR MRI | THE JOHNS HOPKINS UNIVERSITY (US) | 1991-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240216513-A1 | FATTY ACID-BIFUNCTIONAL DEGRADER CONJUGATES AND THEIR METHODS OF USE | FASN, FABP1, SCD | TSHR 2284/4885LMNA 2491/4885ALDH1A1 634/4885 |
| US-20250361250-A1 | FLUORINE-CONTAINING SILANE COMPOUND | FLI1, AFF1, RFT1 | TSHR 2035/4885LMNA 1768/4885ALDH1A1 879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.