SCHEMBL4006166

SCHEMBL4006166

COC(=O)CCCCCCCCCCCBr

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.67
LMNA P02545 3/20 0.57
ALDH1A1 P00352 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.49
KMT2A Q03164 3/20 0.47
RECQL P46063 1/20 0.46
EPHX2 P34913 2/20 0.43
MEN1 O00255 2/20 0.43
POLB P06746 1/20 0.42
POLA1 P09884 1/20 0.42
HPGD P15428 1/20 0.42
CA12 O43570 1/20 0.41
CA14 Q9ULX7 1/20 0.41
DGKA P23743 1/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31049868 1.00 TSHR (0.67) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL1365242 1.00 TSHR (0.67) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL11849992 1.00 TSHR (0.67) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL16719251 1.00 TSHR (0.67) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL1115015 1.00 TSHR (0.67) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL8973175 1.00 TSHR (0.67) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL1365853 1.00 TSHR (0.67) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL1285241 1.00 TSHR (0.67) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL454130 1.00 TSHR (0.67) TSHRLMNAALDH1A1L3MBTL1KMT2A
SCHEMBL31734806 1.00 TSHR (0.67) TSHRLMNAALDH1A1L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119605800-A Oilfield water injection bactericide containing plant sterilization component and preparation method thereof 郑州德融科技有限公司 2025-03-14 CN claimed
CN-122055150-A Cyproheptadine derivatives 思凯生科股份有限公司 2026-05-15 CN disclosed
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-19 US disclosed
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-12 US disclosed
EP-3638678-B1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS MODERNATX INC (US) 2025-12-03 EP disclosed
US-20250361250-A1 FLUORINE-CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2025-11-27 US disclosed
EP-4186888-B1 COMPOUND AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2025-11-26 EP disclosed
EP-4036079-B1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF AGENTS MODERNATX INC (US) 2025-11-19 EP disclosed
US-12404232-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-09-02 US disclosed
US-12396961-B2 Compounds and compositions for intracellular delivery of agents MODERNATX, INC. (US) 2025-08-26 US disclosed
EP-0473871-B1 Fluorine-containing compounds MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1996-02-07 EP disclosed
EP-0576603-A1 PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC HYPERPLASIA, CONTAINING A 5 ALPHA-REDUCTASE INHIBITOR AND AN ANTIANDROGEN MERCK & CO. INC. (US) 1994-01-05 EP disclosed
US-5266724-A Magnetic recording media lubricant MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1993-11-30 US disclosed
US-5188747-A Utilized in magnetic recording media for lubrication and rust prevention MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1993-02-23 US disclosed
EP-0525888-A1 New catechol type non-steroidal drugs as 5-alpha reductase inhibitors MERCK & CO. INC. (US) 1993-02-03 EP disclosed
WO-1992018132-A1 PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA COMTAINING A 5 ALPHA-REDUCTASE INHIBITOR MERCK & CO., INC. (US) 1992-10-29 WO disclosed
WO-1992016213-A1 PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC HYPERPLASIA, CONTAINING A 5 ALPHA-REDUCTASE INHIBITOR AND AN ANTIANDROGEN MERCK & CO., INC. (US) 1992-10-01 WO disclosed
WO-1992016233-A1 PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC CANCER CONTAINING A 5 ALPHA REDUCTASE INHIBITOR AND AN ANTIANDROGEN MERCK & CO., INC. (US) 1992-10-01 WO disclosed
EP-0473871-A2 Fluorine-containing compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1992-03-11 EP disclosed
US-4122276-A FOR MAKING CONDENSATION POLYMERS CONTAINING HYDANTOIN CIBA-GEIGY CORPORATION (US) 1978-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12396961-B2 Compounds and compositions for intracellular delivery of agents LNPK, PLTP, PHOSPHO1 TSHR 3222/4885LMNA 1403/4885ALDH1A1 4687/4885
US-20260078082-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS PHOSPHO1, LIPC, SDCBP TSHR 4134/4885LMNA 455/4885ALDH1A1 4429/4885
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS SIN3A, PLIN3, MSR1 TSHR 540/4885LMNA 1487/4885ALDH1A1 4755/4885
US-20250361250-A1 FLUORINE-CONTAINING SILANE COMPOUND FLI1, AFF1, RFT1 TSHR 2035/4885LMNA 1768/4885ALDH1A1 879/4885
US-12404232-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 TSHR 3089/4885LMNA 1539/4885ALDH1A1 4530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.