Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 6/20 | 0.33 |
| ▸ | RAB9A | P51151 | 6/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 2/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8960851 | 0.89 | ACACB (0.36) | ACACBMEN1KMT2AMAPTKDM4E | |
| SCHEMBL8961018 | 0.86 | HAO1 (0.38) | ACACBMAPTKDM4EAPPESR1 | |
| SCHEMBL8960877 | 0.84 | ACACB (0.35) | ACACBMAPTKDM4EAPPESR1 | |
| SCHEMBL8961152 | 0.84 | ACACB (0.35) | ACACBMAPTKDM4EAPPESR1 | |
| SCHEMBL8961298 | 0.83 | ACACB (0.34) | ACACBMAPTKDM4EAPPESR1 | |
| SCHEMBL8961282 | 0.82 | ACACB (0.34) | ACACBMAPTKDM4EAPPESR1 | |
| SCHEMBL8961072 | 0.82 | ACACB (0.34) | ACACBMAPTKDM4EAPPPPARA | |
| SCHEMBL8961084 | 0.81 | FFAR1 (0.48) | ACACBKDM4ELMNA | |
| SCHEMBL8973217 | 0.80 | ALDH1A1 (0.34) | ACACBMEN1KMT2AKDM4EESR1 | |
| SCHEMBL8961296 | 0.80 | CYP1A1 (0.47) | ACACBMAPTKDM4EAPPESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566455-B1 | Derivatives of 7-ethynyle alpha-(methoxymethylene)1-naphthalenacetic acid, their process of preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-03-06 | — | — | EP | disclosed |
| US-5451696-A | Parasiticide intermediate | ROUSSEL-UCLAF (FR) | 1995-09-19 | — | — | US | disclosed |
| US-5380883-A | Insecticide, nematocide, miticide | ROUSSEL-UCLAF (FR) | 1995-01-10 | — | — | US | disclosed |
| EP-0566455-A1 | Derivatives of 7-ethynyle alpha-(methoxymethylene)1-naphthalenacetic acid, their process of preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-10-20 | — | — | EP | disclosed |