Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8961018 | 0.87 | HAO1 (0.38) | ACACBHAO1PPARAPTPN11FFAR1 | |
| SCHEMBL8960955 | 0.84 | ACACB (0.37) | ACACBHAO1PPARAPTPN11RAB9A | |
| SCHEMBL8960877 | 0.78 | ACACB (0.35) | ACACBHAO1PPARAFFAR1MAPT | |
| SCHEMBL8961152 | 0.78 | ACACB (0.35) | ACACBPPARAFFAR1MAPTTBXA2R | |
| SCHEMBL8961298 | 0.77 | ACACB (0.34) | ACACBPPARAFFAR1MAPTTBXA2R | |
| SCHEMBL8961282 | 0.76 | ACACB (0.34) | ACACBHAO1PPARAFFAR1MAPT | |
| SCHEMBL8961072 | 0.76 | ACACB (0.34) | ACACBPPARAFFAR1MAPT | |
| SCHEMBL8960851 | 0.76 | ACACB (0.36) | ACACBPPARARAB9AFFAR1MEN1 | |
| SCHEMBL8973237 | 0.74 | ACACB (0.35) | ACACBPPARARAB9AMEN1MAPT | |
| SCHEMBL8961084 | 0.74 | FFAR1 (0.48) | ACACBPTPN11FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566455-B1 | Derivatives of 7-ethynyle alpha-(methoxymethylene)1-naphthalenacetic acid, their process of preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1996-03-06 | — | — | EP | disclosed |
| US-5451696-A | Parasiticide intermediate | ROUSSEL-UCLAF (FR) | 1995-09-19 | — | — | US | disclosed |
| US-5380883-A | Insecticide, nematocide, miticide | ROUSSEL-UCLAF (FR) | 1995-01-10 | — | — | US | disclosed |
| EP-0566455-A1 | Derivatives of 7-ethynyle alpha-(methoxymethylene)1-naphthalenacetic acid, their process of preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-10-20 | — | — | EP | disclosed |