Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637931 | 0.76 | MAPK1 (0.58) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL9608405 | 0.76 | MEN1 (0.62) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL8847537 | 0.74 | MEN1 (0.54) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL21352426 | 0.73 | TSHR (0.63) | ALDH1A1KDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9608496 | 0.73 | MAPT (0.56) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL13938620 | 0.73 | PTPN1 (0.50) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL195530 | 0.72 | SMN1; SMN2 (0.71) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL29502789 | 0.72 | SMN1; SMN2 (0.71) | ALDH1A1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL1009146 | 0.72 | PKM (0.58) | ALDH1A1HSD17B10SMN1; SMN2TSHRTRPM8 | |
| SCHEMBL29592621 | 0.72 | PKM (0.58) | ALDH1A1HSD17B10SMN1; SMN2TSHRTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502189-A | STABILIZERS FOR PLASTICS AND POLYMERS, AUTOMOTIVE COATINGS | CIBA-GEIGY CORPORATION (US) | 1996-03-26 | — | — | US | disclosed |
| US-5229512-A | Stabilizers | CIBA-GEIGY CORPORATION (US) | 1993-07-20 | — | — | US | disclosed |
| EP-0453405-A1 | Compounds containing o-hydroxyphenyl-1,3,5-triazines and sterile inhibited amines | CIBA-GEIGY AG (CH) | 1991-10-23 | — | — | EP | disclosed |