SCHEMBL8973406

SCHEMBL8973406

Clc1ccccc1Cc1c[nH]c(-c2ccccc2)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.40
MAPT P10636 2/20 0.40
LMNA P02545 2/20 0.40
KDM4E B2RXH2 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
TP53 P04637 1/20 0.40
PNP P00491 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
HTR2C P28335 1/20 0.39
HTR2B P41595 1/20 0.39
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
DAO P14920 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
TAAR1 Q96RJ0 2/20 0.38
RAB9A P51151 1/20 0.37
ATM Q13315 1/20 0.37
NR1H2 P55055 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8973353 0.87 MAPT (0.43) L3MBTL1MAPTLMNAKDM4ESMN1; SMN2
SCHEMBL8973626 0.81 GABRA1 (0.55) L3MBTL1MAPTLMNAKDM4ESMN1; SMN2
SCHEMBL17622 0.78 CXCR2 (0.42) L3MBTL1KDM4ESMN1; SMN2ALDH1A1POLB
SCHEMBL8973308 0.78 GABRA1 (0.43) PNPADORA2AADORA1GABRA1GABRB2
SCHEMBL10792280 0.78 SMN1; SMN2 (0.49) L3MBTL1MAPTLMNAKDM4ESMN1; SMN2
Hydrochloric Acid SCHEMBL8588873 0.77 CXCR2 (0.41) L3MBTL1KDM4ESMN1; SMN2ALDH1A1POLB
SCHEMBL10792377 0.75 ADORA2A (0.42) L3MBTL1MAPTLMNAKDM4ESMN1; SMN2
SCHEMBL672597 0.74 NOTUM (0.42) L3MBTL1KDM4EALDH1A1POLBRAB9A
SCHEMBL2780530 0.74 POLB (0.41) L3MBTL1MAPTKDM4ESMN1; SMN2TP53
SCHEMBL2092717 0.73 MTOR (0.38) L3MBTL1MAPTKDM4ESMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5560785-A TREATING SURFACE WITH SOLUTION OF IMIDAZOLE COMPOUND, COPPER COMPOUND, ZINC COMPOUND, STABILIZERS SHIKOKU CHEMICALS CORPORATION (JP) 1996-10-01 US disclosed
US-5498301-A ON A PRINTED WIRING BOARD, HEAT RESISTANT, MOISTURE RESISTANT, A 2-ARYLIMIDAZOLE, CARBOXYLIC ACID, AMMONIA, WATER SHIKOKU CHEMICALS CORPORATION (JP) 1996-03-12 US disclosed
EP-0627499-A1 Agent for treating surfaces of copper and copper alloys SHIKOKU CHEMICALS CORPORATION (JP) 1994-12-07 EP disclosed