Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26077857 | 1.00 | TAAR1 (0.34) | TAAR1SLC6A2SLC6A3MAOASLC6A4 | |
| SCHEMBL25893969 | 0.83 | — | — | |
| SCHEMBL13859897 | 0.79 | — | — | |
| SCHEMBL27805189 | 0.79 | — | — | |
| SCHEMBL13272376 | 0.79 | TSHR (0.31) | — | |
| SCHEMBL17553410 | 0.78 | — | — | |
| SCHEMBL7764187 | 0.76 | TAAR1 (0.38) | TAAR1SLC6A2SLC6A3SLC6A4SIGMAR1 | |
| SCHEMBL18567232 | 0.76 | ALPI (0.31) | — | |
| SCHEMBL10161458 | 0.76 | EPHX1 (0.31) | — | |
| SCHEMBL20626960 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188260-B2 | Versatile acylation catalytic RNAs and uses thereof | THE UNIVERSITY OF TOKYO (JP) | 2012-05-29 | — | — | US | disclosed |