Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22652556 | 0.84 | — | — | |
| SCHEMBL3504346 | 0.84 | SLC7A5 (0.43) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL879605 | 0.84 | SLC7A5 (0.43) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL24538484 | 0.84 | SLC7A5 (0.32) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL23869542 | 0.77 | — | — | |
| SCHEMBL10161458 | 0.76 | EPHX1 (0.31) | — | |
| SCHEMBL26077857 | 0.76 | TAAR1 (0.34) | — | |
| SCHEMBL8973472 | 0.76 | TAAR1 (0.34) | — | |
| SCHEMBL12153681 | 0.74 | APAF1 (0.33) | — | |
| SCHEMBL12831690 | 0.72 | NAMPT (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788359-B1 | COMPOSITION AND METHOD FOR NEUROPEPTIDE S RECEPTOR (NPSR) ANTAGONISTS | RES TRIANGLE INST (US) | 2017-03-01 | — | — | EP | disclosed |