Levacetylleucine

Levacetylleucine

SCHEMBL8973550

CC(=O)N[C@@H](CC(C)C)C(=O)O.OCNCCc1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
ANPEP P15144 1/20 0.52
LTA4H P09960 1/20 0.52
MME P08473 2/20 0.51
CPA1 P15085 3/20 0.50
CPA2 P48052 3/20 0.50
CPA4 Q9UI42 3/20 0.50
MEN1 O00255 1/20 0.46
TSHR P16473 1/20 0.46
KMT2A Q03164 1/20 0.46
CPB1 P15086 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2632695 0.81 CPA1 (0.62) ALDH1A1LTA4HMMECPA1CPA2
SCHEMBL5870044 0.79 ANPEP (0.80) ALDH1A1ANPEPMMEMEN1TSHR
SCHEMBL8255279 0.79 ANPEP (0.80) ALDH1A1ANPEPMMEMEN1TSHR
SCHEMBL15692325 0.77 MME (0.69) ALDH1A1LTA4HMMECPA1CPA2
SCHEMBL31326264 0.77 MME (0.69) ALDH1A1LTA4HMMECPA1CPA2
SCHEMBL2632703 0.77 CPA1 (0.61) ALDH1A1MMECPA1CPA2CPA4
SCHEMBL7272374 0.75 MME (0.58) ANPEPLTA4HMME
SCHEMBL8078351 0.75 MME (0.58) ANPEPLTA4HMME
Levacetylleucine SCHEMBL714003 0.75 ALDH1A1 (1.00) ALDH1A1MEN1KMT2A
Acetylleucine SCHEMBL282371 0.75 ALDH1A1 (1.00) ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0543310-B1 Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same SUNTORY LTD (JP) 1996-03-27 EP disclosed
EP-0543310-A2 Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same SUNTORY LIMITED (JP) 1993-05-26 EP disclosed