Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30645031 | 1.00 | GAA (0.59) | GAATDP1L3MBTL1RECQLALDH1A1 | |
| SCHEMBL16938605 | 0.98 | TDP1 (0.59) | GAATDP1L3MBTL1RECQLALDH1A1 | |
| SCHEMBL30562288 | 0.95 | GAA (0.61) | GAATDP1L3MBTL1RECQLALDH1A1 | |
| SCHEMBL3066754 | 0.88 | GAA (0.65) | GAATDP1L3MBTL1RECQLALDH1A1 | |
| SCHEMBL8973932 | 0.88 | GAA (0.53) | GAATDP1L3MBTL1RECQLALDH1A1 | |
| SCHEMBL8816370 | 0.86 | TDP1 (0.57) | GAATDP1L3MBTL1RECQLALDH1A1 | |
| SCHEMBL24507059 | 0.86 | GAA (0.71) | GAATDP1RECQLALDH1A1CYP1A2 | |
| SCHEMBL6570943 | 0.84 | GAA (0.74) | GAATDP1RECQLALDH1A1CYP1A2 | |
| SCHEMBL12670609 | 0.83 | GAA (0.58) | GAATDP1L3MBTL1RECQLALDH1A1 | |
| SCHEMBL7455967 | 0.81 | GAA (0.60) | GAATDP1RECQLALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250332124-A1 | MITOFUSIN ACTIVATORS HAVING AN ENDOCYCLIC-BONDED CARBONYL GROUP AND METHODS FOR USE THEREOF | DORN II GERALD W (US) | 2025-10-30 | — | — | US | disclosed |
| US-12396968-B2 | Mitofusin activators having an endocyclic-bonded carbonyl group and methods for use thereof | DORN II GERALD W (US) | 2025-08-26 | — | — | US | disclosed |
| US-20240050386-A1 | MITOFUSIN ACTIVATORS HAVING AN ENDOCYCLIC-BONDED CARBONYL GROUP AND METHODS FOR USE THEREOF | DORN II GERALD W (US) | 2024-02-15 | — | — | US | disclosed |
| WO-2023196340-A1 | MITOFUSIN ACTIVATORS HAVING AN ENDOCYCLIC-BONDED CARBONYL GROUP AND METHODS FOR USE THEREOF | DORN II GERALD W (US) | 2023-10-12 | — | — | WO | disclosed |
| EP-0456089-B1 | Cyclohexenonoximethers, process for their production and their application as herbicides | BASF AG (DE) | 1996-04-03 | — | — | EP | disclosed |
| US-5364833-A | Controlling grasses in wheat and rice crops | BASF AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | disclosed |
| EP-0456089-A1 | Cyclohexenonoximethers, process for their production and their application as herbicides | BASF Aktiengesellschaft (DE) | 1991-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12396968-B2 | Mitofusin activators having an endocyclic-bonded carbonyl group and methods for use thereof | MFN2, CYCS, CYC1 | GAA 2958/4885TDP1 4447/4885L3MBTL1 4238/4885 |
| US-20240050386-A1 | MITOFUSIN ACTIVATORS HAVING AN ENDOCYCLIC-BONDED CARBONYL GROUP AND METHODS FOR USE THEREOF | MFN2, CYCS, CYC1 | GAA 2958/4885TDP1 4447/4885L3MBTL1 4238/4885 |
| US-20250332124-A1 | MITOFUSIN ACTIVATORS HAVING AN ENDOCYCLIC-BONDED CARBONYL GROUP AND METHODS FOR USE THEREOF | MFN2, CYCS, CYC1 | GAA 2941/4885TDP1 4460/4885L3MBTL1 4239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.