Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 6/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532760 | 1.00 | EPHX1 (0.58) | EPHX1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL11522408 | 1.00 | EPHX1 (0.58) | EPHX1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL11531047 | 1.00 | EPHX1 (0.58) | EPHX1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL11525493 | 1.00 | EPHX1 (0.58) | EPHX1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL6946859 | 0.97 | DGKA (0.56) | EPHX1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL6223307 | 0.95 | DGKA (0.53) | EPHX1DGKAPRSS1PRSS2PRSS3 | |
| SCHEMBL15865169 | 0.90 | EPHX2 (0.59) | DGKAFAAHEPHX2 | |
| SCHEMBL7256775 | 0.89 | EPHX1 (0.47) | EPHX1DGKANAAAACHE | |
| SCHEMBL11527233 | 0.88 | DGKA (0.53) | DGKAPRSS1PRSS2PRSS3FAAH | |
| SCHEMBL29137394 | 0.88 | DGKA (0.53) | DGKAPRSS1PRSS2PRSS3FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554485-A | PHOTORESISTS | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |
| US-5401614-A | Photolithography | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1995-03-28 | — | — | US | disclosed |
| US-5380621-A | Multilayer photoresists with antireflective layers and developers | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1995-01-10 | — | — | US | disclosed |