SCHEMBL8973657

SCHEMBL8973657

C#CC(F)c1ccc2c(c1)CCC2N.[Au]

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL333101 0.98 ESR1 (0.31) ESR1ESR2
Hydrochloric Acid SCHEMBL7337175 0.97 ACHE (0.32) ESR1ESR2
SCHEMBL332173 0.87 ACHE (0.37)
Hydrochloric Acid SCHEMBL7342057 0.85 ACHE (0.39)
SCHEMBL29854642 0.81 ESR1 (0.34) ESR1ESR2
SCHEMBL31136551 0.81 ESR1 (0.34) ESR1ESR2
SCHEMBL27203887 0.81 ESR1 (0.34) ESR1ESR2
SCHEMBL5003615 0.81 ESR1 (0.33) ESR1ESR2
SCHEMBL21067299 0.81 ESR1 (0.33) ESR1ESR2
Hydrochloric Acid SCHEMBL30809644 0.80 ACHE (0.35) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5486541-A FOR TREATING PARKINSON*S DISEASE, MEMORY DISORDERS, ALZHEIMER*S DISEASE, DEPRESSION OR HYPERACTIVE SYNDROME TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 1996-01-23 US disclosed