Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | LAP3 | P28838 | 5/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 3/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL1758770 | 0.77 | SLC7A5 (0.79) | SLC7A5LAP3ANPEPSLC1A3SLC1A2 | |
| Valine SCHEMBL29415345 | 0.77 | SLC7A5 (0.79) | SLC7A5LAP3ANPEPSLC1A3SLC1A2 | |
| Valine SCHEMBL16010343 | 0.77 | SLC7A5 (0.79) | SLC7A5LAP3ANPEPSLC1A3SLC1A2 | |
| Valine SCHEMBL1758768 | 0.77 | SLC7A5 (0.79) | SLC7A5LAP3ANPEPSLC1A3SLC1A2 | |
| Medronic Acid SCHEMBL1614267 | 0.76 | SLC7A5 (0.68) | SLC7A5LAP3GRIN2DGRIN3BGRIN1 | |
| Threonine SCHEMBL8934992 | 0.75 | SLC7A5 (0.52) | SLC7A5LAP3ANPEPSLC1A3SLC1A2 | |
| Threonine SCHEMBL28875922 | 0.75 | SLC7A5 (0.52) | SLC7A5LAP3ANPEPSLC1A3SLC1A2 | |
| Threonine SCHEMBL1193769 | 0.75 | SLC7A5 (0.52) | SLC7A5LAP3ANPEPSLC1A3SLC1A2 | |
| Threonine SCHEMBL917908 | 0.75 | SLC7A5 (0.52) | SLC7A5LAP3ANPEPSLC1A3SLC1A2 | |
| SCHEMBL417728 | 0.75 | SLC7A5 (0.46) | SLC7A5LAP3ANPEPERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500420-A | Metabotropic glutamate receptor agonists in the treatment of cerebral ischemia | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-03-19 | — | — | US | disclosed |