Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489892 | 0.83 | RAPGEF4 (0.49) | RAPGEF4F2GAAGRM4KMT2A | |
| SCHEMBL4911297 | 0.81 | TSHR (0.61) | RAPGEF4TSHRNFKB1GAAMAPT | |
| SCHEMBL8973245 | 0.78 | TSHR (0.61) | TSHRNFKB1GAAMAPTKMT2A | |
| SCHEMBL8973265 | 0.78 | TSHR (0.56) | RAPGEF4TSHRNFKB1GAAMAPT | |
| SCHEMBL10939229 | 0.78 | TSHR (0.67) | TSHRNFKB1MAPTKMT2AKDM4E | |
| SCHEMBL6531807 | 0.77 | CHRNA7 (0.51) | GAAMAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL13938683 | 0.77 | MAPK14 (0.47) | — | |
| SCHEMBL9010642 | 0.77 | CA12 (0.46) | TSHRNFKB1GAAALDH1A1 | |
| SCHEMBL3243118 | 0.77 | LCK (0.49) | — | |
| SCHEMBL6760243 | 0.76 | AKR1C3 (0.42) | TSHRNFKB1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5561131-A | INCREASING THE WOOL GROWTH BY ADMINISTERING AN ANTIPROTOZOA AGENT TO SHEEP | MALLINCKRODT VETERINARY, INC. (US) | 1996-10-01 | — | — | US | disclosed |
| EP-0661976-A1 | DEFAUNATION METHOD | MALLINCKRODT VETERINARY LIMITED (AU) | 1995-07-12 | — | — | EP | disclosed |
| EP-0661976-A4 | DEFAUNATION METHOD. | MALLINCKRODT VETERINARY LTD (AU) | 1994-07-20 | — | — | EP | disclosed |
| WO-1993002680-A1 | DEFAUNATION METHOD | PITMAN-MOORE AUSTRALIA LIMITED (AU) | 1993-02-18 | — | — | WO | disclosed |