SCHEMBL8973706

SCHEMBL8973706

CCCC(=O)OC(CC)CO

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.60
MAPK1 P28482 1/20 0.60
PRKCA P17252 5/20 0.51
PRKCE Q02156 2/20 0.51
PRKCQ Q04759 2/20 0.51
PRKCD Q05655 2/20 0.51
ALDH1A1 P00352 3/20 0.47
FAAH O00519 1/20 0.47
HPGD P15428 1/20 0.47
CNR1 P21554 1/20 0.47
CNR2 P34972 1/20 0.47
LMNA P02545 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76959 0.91 MAPT (0.70) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL2719944 0.89 ALDH1A1 (0.52) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL25902488 0.84 MAPT (0.86) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL13176700 0.84 MAPT (0.86) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL25902502 0.84 MAPT (0.86) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL15308954 0.84 MAPT (0.86) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL13110319 0.84 MAPT (0.86) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL18623392 0.84 MAPT (0.86) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL13110719 0.84 MAPT (0.86) MAPTMAPK1PRKCAPRKCEPRKCQ
SCHEMBL25902497 0.84 MAPT (0.86) MAPTMAPK1PRKCAPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4074518-B1 RESIN COMPOSITION, RESIN-METAL COMPOSITE MEMBER, AND TIRE BRIDGESTONE CORP (JP) 2023-10-18 EP disclosed
EP-3608128-B1 RESIN-METAL COMPOSITE MEMBER FOR TIRE, AND TIRE BRIDGESTONE CORP (JP) 2023-09-27 EP disclosed
CN-110997605-B Synthesis of diols by transfer hydrogenation of alpha-functionalized esters with alcohols 伊士曼化工公司 2023-07-25 CN disclosed
EP-3702174-B1 METAL RESIN COMPOSITE MEMBER FOR TIRES, AND TIRE BRIDGESTONE CORP (JP) 2023-05-17 EP disclosed
US-20230023212-A1 RESIN COMPOSITION, RESIN-METAL COMPOSITE MEMBER, AND TIRE BRIDGESTONE CORPORATION (JP) 2023-01-26 US disclosed
EP-4074518-A1 RESIN COMPOSITION, RESIN/METAL COMPOSITE MEMBER, AND TIRE BRIDGESTONE CORPORATION (JP) 2022-10-19 EP disclosed
EP-3611033-B1 TIRE, AND METHOD FOR MANUFACTURING TIRE BRIDGESTONE CORP (JP) 2022-05-04 EP disclosed
EP-3640049-B1 RESIN-METAL COMPOSITE MEMBER FOR TIRE, AND TIRE BRIDGESTONE CORP (JP) 2022-02-23 EP disclosed
US-20220033644-A1 RESIN COMPOSITION FOR TIRE, RESIN-METAL COMPOSITE MEMBER FOR TIRE, AND TIRE BRIDGESTONE CORPORATION (JP) 2022-02-03 US disclosed
EP-3640051-B1 RESIN-METAL COMPOSITE MEMBER FOR TIRE, AND TIRE BRIDGESTONE CORP (JP) 2022-01-05 EP disclosed
US-20160152079-A1 TIRE BRIDGESTONE CORPORATION (JP) 2016-06-02 US disclosed
US-20160075182-A1 TIRE BRIDGESTONE CORPORATION (JP) 2016-03-17 US disclosed
EP-2990220-A1 TIRE Bridgestone Corporation (JP) 2016-03-02 EP disclosed
EP-2990221-A1 TIRE Bridgestone Corporation (JP) 2016-03-02 EP disclosed
US-20160001598-A1 TIRE BRIDGESTONE CORPORATION (JP) 2016-01-07 US disclosed
EP-2962869-A1 TIRE Bridgestone Corporation (JP) 2016-01-06 EP disclosed
CN-104144801-A Tire BRIDGESTONE CORP 2014-11-12 CN disclosed
EP-0372891-B1 Optically active compounds and a process for producing these compounds CHISSO CORP (JP) 1996-03-13 EP disclosed
US-5391494-A Process for selectively producing optically active 1-derivatized-2-diol using lipase CES and triglyceride CHISSO CORPORATION (JP) 1995-02-21 US disclosed
EP-0372891-A2 Optically active compounds and a process for producing these compounds CHISSO CORPORATION (JP) 1990-06-13 EP disclosed