Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | KDM4B | O94953 | 2/20 | 0.36 |
| ▸ | KDM5C | P41229 | 2/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10403386 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| SCHEMBL2897055 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| SCHEMBL10403385 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL6694657 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| Potassium Ion SCHEMBL10465811 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| SCHEMBL6694654 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| SCHEMBL27662308 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL11569999 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| SCHEMBL8974104 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MEN1NPC1MAPTRAB9A | |
| SCHEMBL27807523 | 0.78 | MAPT (0.44) | ALDH1A1MEN1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484928-A | 2-(2-aminothiazol-4-yl)-2-oxoacetic acid derivatives | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1996-01-16 | — | — | US | claimed |