SCHEMBL8974384

SCHEMBL8974384

O=C(C=COC=CC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.57
LMNA P02545 3/20 0.57
BCHE P06276 3/20 0.57
RECQL P46063 2/20 0.57
PLIN1 O60240 2/20 0.57
PLIN5 Q00G26 2/20 0.57
ABHD5 Q8WTS1 2/20 0.57
MAOB P27338 2/20 0.57
TNFRSF1A P19438 1/20 0.57
ACHE P22303 1/20 0.57
CYP1B1 Q16678 1/20 0.57
ALDH1A1 P00352 4/20 0.54
MAPK1 P28482 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
AKT1 P31749 3/20 0.53
RAB9A P51151 4/20 0.52
NFKB1 P19838 3/20 0.52
NFKB2 Q00653 3/20 0.52
RELA Q04206 3/20 0.52
NPSR1 Q6W5P4 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2954324 0.83 MAPT (0.70) MAPTLMNABCHERECQLPLIN1
SCHEMBL2954318 0.83 MAPT (0.70) MAPTLMNABCHERECQLPLIN1
SCHEMBL11073619 0.83 MAPT (0.70) MAPTLMNABCHERECQLPLIN1
SCHEMBL7529869 0.83 AKT1 (0.59) MAPTLMNABCHERECQLPLIN1
SCHEMBL11882381 0.83 AKT1 (0.59) MAPTLMNABCHERECQLPLIN1
SCHEMBL1875162 0.83 AKT1 (0.59) MAPTLMNABCHERECQLPLIN1
SCHEMBL12963902 0.81 MAPT (0.52) MAPTLMNABCHERECQLPLIN1
SCHEMBL15486166 0.79 RECQL (0.52) MAPTLMNABCHERECQLPLIN1
SCHEMBL10275628 0.78 AKT1 (0.54) MAPTLMNABCHERECQLPLIN1
SCHEMBL10439177 0.78 AKT1 (0.54) MAPTLMNABCHERECQLPLIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4179584-A None JP disclosed
EP-0500372-B1 Thermal transfer image recording material and method of its production KONISHIROKU PHOTO IND (JP) 1996-04-10 EP disclosed
US-5358582-A ID card and method of its production KONICA CORPORATION (JP) 1994-10-25 US disclosed
US-5254525-A Thermal transfer image recording material and method of its production KONICA CORPORATION (JP) 1993-10-19 US disclosed
JP-H04179584-A IMAGE RECEIVING SHEET FOR HEAT-SENSITIVE TRANSFER RECORDING KONICA CORP 1992-06-26 JP disclosed
EP-0147747-B1 HEAT-TRANSFER IMAGE-RECEIVING ELEMENT KONICA CORPORATION (JP) 1990-06-06 EP disclosed
US-4840870-A DISCOLORATION INHIBITION KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1989-06-20 US disclosed
EP-0147747-A2 Heat-transfer image-receiving element KONICA CORPORATION (JP) 1985-07-10 EP disclosed