Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | RECQL | P46063 | 2/20 | 0.70 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.70 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.70 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.70 |
| ▸ | MAOB | P27338 | 2/20 | 0.70 |
| ▸ | BCHE | P06276 | 1/20 | 0.70 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.70 |
| ▸ | ACHE | P22303 | 1/20 | 0.70 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | AKT1 | P31749 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954318 | 1.00 | MAPT (0.70) | MAPTLMNARECQLPLIN1PLIN5 | |
| SCHEMBL2954324 | 1.00 | MAPT (0.70) | MAPTLMNARECQLPLIN1PLIN5 | |
| SCHEMBL312430 | 0.92 | ALDH1A1 (0.68) | MAPTLMNARECQLPLIN1PLIN5 | |
| SCHEMBL5585936 | 0.92 | ALDH1A1 (0.68) | MAPTLMNARECQLPLIN1PLIN5 | |
| SCHEMBL312429 | 0.92 | ALDH1A1 (0.68) | MAPTLMNARECQLPLIN1PLIN5 | |
| SCHEMBL10876318 | 0.90 | ALDH1A1 (0.65) | MAPTLMNARECQLPLIN1PLIN5 | |
| SCHEMBL10936319 | 0.88 | MAPT (0.57) | MAPTLMNARECQLPLIN1PLIN5 | |
| SCHEMBL10936322 | 0.88 | MAPT (0.57) | MAPTLMNARECQLPLIN1PLIN5 | |
| SCHEMBL3887709 | 0.88 | RECQL (0.59) | MAPTLMNARECQLPLIN1PLIN5 | |
| SCHEMBL29130651 | 0.88 | MAPT (0.57) | MAPTLMNARECQLPLIN1PLIN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439418-A | UNSATURATED ARYL KETONE | HENKEL KGAA (DE) | 1984-03-27 | — | — | US | disclosed |