Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8974519 | 1.00 | PTPN1 (0.36) | PTPN1ALDH1A1MEN1KMT2AATM | |
| SCHEMBL8974484 | 1.00 | PTPN1 (0.36) | PTPN1ALDH1A1MEN1KMT2AATM | |
| SCHEMBL8973833 | 0.93 | PTPN1 (0.34) | PTPN1ALDH1A1MEN1KMT2AATM | |
| SCHEMBL8973970 | 0.93 | PTPN1 (0.34) | PTPN1ALDH1A1MEN1KMT2AATM | |
| SCHEMBL8973830 | 0.93 | PTPN1 (0.34) | PTPN1ALDH1A1MEN1KMT2AATM | |
| SCHEMBL2746637 | 0.87 | ALOX5 (0.38) | ALDH1A1MEN1KMT2AATMKDM4E | |
| SCHEMBL8974918 | 0.87 | ALOX5 (0.38) | ALDH1A1MEN1KMT2AATMKDM4E | |
| SCHEMBL2746634 | 0.87 | ALOX5 (0.38) | ALDH1A1MEN1KMT2AATMKDM4E | |
| SCHEMBL8974999 | 0.85 | PTPN1 (0.35) | PTPN1ALDH1A1MEN1KMT2AATM | |
| SCHEMBL8974986 | 0.85 | PTPN1 (0.35) | PTPN1ALDH1A1MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5527948-A | SUBSTITUTED NAPHTHYL-ALKENOIC ACIDS FOR TREATING AUTOIMMUNE DISORDERS | EISAI CORP. LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| US-5298649-A | Antiinflammatory agents, rheumatic agents and treatment of autoimmune diseases | EISAI CO., LTD. (JP) | 1994-03-29 | — | — | US | disclosed |
| EP-0376288-B1 | Naphthalene derivative | EISAI CO LTD (JP) | 1994-03-09 | — | — | EP | disclosed |
| US-5134111-A | Inhibitors of interleukin-1 as antiinflammatory agents | EISAI CO., LTD. (JP) | 1992-07-28 | — | — | US | disclosed |
| EP-0376288-A1 | Naphthalene derivative | Eisai Co., Ltd. (JP) | 1990-07-04 | — | — | EP | disclosed |