Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL28887747 | 0.91 | TSHR (0.67) | TSHRHPGDTHRBTDP1L3MBTL1 | |
| Styrene SCHEMBL3196230 | 0.91 | TSHR (0.67) | TSHRHPGDTHRBTDP1L3MBTL1 | |
| Styrene SCHEMBL3696057 | 0.91 | TSHR (0.67) | TSHRHPGDTHRBTDP1L3MBTL1 | |
| Styrene SCHEMBL67823 | 0.91 | TSHR (0.67) | TSHRHPGDTHRBTDP1L3MBTL1 | |
| Styrene SCHEMBL4817683 | 0.90 | TSHR (0.52) | TSHRHPGDTHRBTDP1L3MBTL1 | |
| Styrene SCHEMBL1449849 | 0.90 | TSHR (0.52) | TSHRHPGDTHRBTDP1L3MBTL1 | |
| Styrene SCHEMBL19306537 | 0.90 | TSHR (0.52) | TSHRHPGDTHRBTDP1L3MBTL1 | |
| Itaconate SCHEMBL9173619 | 0.90 | TSHR (0.52) | TSHRHPGDTHRBTDP1L3MBTL1 | |
| Styrene SCHEMBL1563744 | 0.90 | TSHR (0.58) | TSHRHPGDTHRBTDP1L3MBTL1 | |
| Styrene SCHEMBL5484779 | 0.89 | TSHR (0.51) | TSHRHPGDTHRBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409657-B1 | Impact modified thermoplastic blends | NOVACOR CHEM CANADA LTD (CA) | 1996-04-10 | — | — | EP | disclosed |
| US-5336719-A | Blend of a block copolymer and a glassy polymer; packaging, containers or protective coverings | POLYSAR LIMITED (CA) | 1994-08-09 | — | — | US | disclosed |
| US-5252664-A | Blend of block polymer, particulate rubber and clear glassy polymer | POLYSAR LIMITED (CA) | 1993-10-12 | — | — | US | disclosed |
| US-5079296-A | TRANSPARENT TOUGHENED THERMOPLASTICS | POLYSAR LIMITED (CA) | 1992-01-07 | — | — | US | disclosed |
| EP-0409657-A2 | Impact modified thermoplastic blends | NOVACOR CHEMICALS (CANADA) LTD. (CA) | 1991-01-23 | — | — | EP | disclosed |