Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.59 |
| ▸ | DRD4 | P21917 | 8/20 | 0.52 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857239 | 0.86 | HRH3 (0.55) | HRH3DRD4ACLY | |
| SCHEMBL14018436 | 0.81 | DRD4 (0.57) | HRH3DRD4 | |
| SCHEMBL8857234 | 0.78 | DRD4 (0.57) | DRD4 | |
| SCHEMBL8975092 | 0.77 | PPARG (0.47) | HRH3DRD4 | |
| SCHEMBL8974671 | 0.77 | GRM2 (0.60) | — | |
| SCHEMBL8974668 | 0.77 | GRM2 (0.60) | — | |
| SCHEMBL8975043 | 0.77 | GRM2 (0.60) | — | |
| SCHEMBL8975210 | 0.77 | GRM2 (0.60) | — | |
| SCHEMBL8974912 | 0.77 | GRM2 (0.60) | — | |
| SCHEMBL8975062 | 0.77 | GRM2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1065532-C | Thiazolidine and oxazolidine derivatives, their preparation and their medical use | SANKYO CO (JP) | 2001-05-09 | — | — | CN | disclosed |
| US-5578620-A | TREATMENT OF DIABETES AND HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 1996-11-26 | — | — | US | disclosed |
| CN-1132750-A | Thiazolidine and oxazolidine derivatives, their preparation and their medical use | SANKYO CO (JP) | 1996-10-09 | — | — | CN | disclosed |
| EP-0678511-A2 | Thiazolidine and oxazolidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1995-10-25 | — | — | EP | disclosed |