Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.55 |
| ▸ | DRD4 | P21917 | 7/20 | 0.51 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8974642 | 0.86 | HRH3 (0.59) | HRH3DRD4ACLY | |
| SCHEMBL14018436 | 0.80 | DRD4 (0.57) | HRH3DRD4GRM2 | |
| SCHEMBL8857140 | 0.76 | GRM2 (0.60) | GRM2 | |
| SCHEMBL8857512 | 0.76 | GRM2 (0.60) | GRM2 | |
| SCHEMBL8857271 | 0.76 | GRM2 (0.60) | GRM2 | |
| SCHEMBL8857234 | 0.75 | DRD4 (0.57) | DRD4 | |
| SCHEMBL22003799 | 0.71 | HRH3 (1.00) | HRH3DRD4 | |
| SCHEMBL5513197 | 0.71 | ALDH1A1 (0.77) | DRD4GRM2 | |
| SCHEMBL6487223 | 0.71 | ALDH1A1 (0.77) | DRD4GRM2 | |
| SCHEMBL5997443 | 0.71 | ALDH1A1 (0.77) | DRD4GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688823-A | ANTILIPEMIC AGENTS, ANTIGLYCEMIC AGENTS, OBESITY, GLUCOSE TOLERANCE INSUFFICIENCY, INSULIN RESISTANCE AND DIABETIC COMPLICATIONS | SANKYO COMPANY, LIMITED (JP) | 1997-11-18 | — | — | US | disclosed |