Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | LTK | P29376 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL858030 | 0.79 | PDE4A (0.52) | NR4A2AURKAPARP1DAPK3JAK2 | |
| SCHEMBL29416439 | 0.79 | PDE4A (0.52) | NR4A2AURKAPARP1DAPK3JAK2 | |
| SCHEMBL16433258 | 0.79 | KDM4E (0.48) | CYP1A2KDM4ELMNAHSP90AA1MAPT | |
| SCHEMBL13783328 | 0.76 | NR4A2 (0.47) | NR4A2AURKAPARP1DAPK3JAK2 | |
| SCHEMBL2158991 | 0.76 | KDM4E (0.42) | AURKACYP1A2KDM4ELMNAHSP90AA1 | |
| SCHEMBL10292144 | 0.76 | KDM4E (0.31) | KDM4ELMNAHSP90AA1MAPTSMN1; SMN2 | |
| SCHEMBL22221946 | 0.76 | PARP1 (0.44) | AURKAPARP1PRKD3MAP4K4CSF1R | |
| SCHEMBL12846342 | 0.76 | PARP1 (0.44) | AURKAPARP1CYP1A2CYP2A6KDM4E | |
| SCHEMBL10511077 | 0.74 | NR4A2 (0.46) | NR4A2AURKAPARP1DAPK3JAK2 | |
| SCHEMBL22644986 | 0.73 | NR4A2 (0.44) | NR4A2AURKAPARP1DAPK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444445-A | Quinazolinone compound and preparation method thereof | 河北科技大学 | 2023-07-18 | — | — | CN | disclosed |
| EP-0705253-A1 | ARALKYLAMINOQUINAZOLINES | BAYER AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000496-A1 | ARALKYLAMINOQUINAZOLINES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-05 | — | — | WO | disclosed |