Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24473459 | 0.87 | CYP1A2 (0.46) | PARP1HTR1AADRA1DADRA1AADRA1B | |
| Ethoxycarbonyl Group SCHEMBL27863139 | 0.82 | KDM4E (0.39) | PARP1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL16433258 | 0.79 | KDM4E (0.48) | ADRA1ACYP1A2KMT2AMEN1ALDH1A1 | |
| SCHEMBL8404378 | 0.79 | PARP1 (0.47) | PARP1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL3507559 | 0.77 | HTR1A (0.49) | HTR1AADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL8974755 | 0.76 | NR4A2 (0.47) | PARP1HTR1ACYP1A2CYP2A6KMT2A | |
| SCHEMBL28534676 | 0.76 | PARP1 (0.44) | PARP1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL22221946 | 0.76 | PARP1 (0.44) | PARP1SSTR4KDM4EMAPTAURKA | |
| SCHEMBL3763540 | 0.76 | PDE4A (0.48) | PARP1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL10292144 | 0.76 | KDM4E (0.31) | KMT2AMEN1HTTKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115651054-B | Steroid compound, application and preparation method thereof | 成都康弘药业集团股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-116589521-A | Steroid compound, application and preparation method thereof | 成都康弘药业集团股份有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-116425819-A | Steroid compound, application and preparation method thereof | 成都康弘药业集团股份有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116059215-A | Steroid compound, application and preparation method thereof | 成都康弘药业集团股份有限公司 | 2023-05-05 | — | — | CN | disclosed |
| US-20220089637-A1 | STEROID COMPOUND, AND USE THEREOF AND PREPARATION METHOD THEREFOR | Chengdu kanghong pharmaceutical co ltd (CN) | 2022-03-24 | — | — | US | disclosed |
| US-20220013735-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2022-01-13 | — | — | US | disclosed |
| EP-3909967-A1 | STEROID COMPOUND, AND USE THEREOF AND PREPARATION METHOD THEREFOR | Chengdu Kanghong Pharmaceutical Group Co., Ltd. (CN) | 2021-11-17 | — | — | EP | disclosed |
| WO-2020143640-A1 | STEROID COMPOUND, AND USE THEREOF AND PREPARATION METHOD THEREFOR | 成都康弘药业集团股份有限公司 | 2020-07-16 | — | — | WO | disclosed |
| US-9822108-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-11-21 | — | — | US | disclosed |
| US-9822108-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-11-21 | — | — | US | disclosed |
| US-20140350024-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2014-11-27 | — | — | US | disclosed |
| US-20140350024-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2014-11-27 | — | — | US | disclosed |
| WO-2013106756-A2 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-07-18 | — | — | WO | disclosed |
| US-20110053932-A1 | Protein Kinase Inhibitors and Methods for Using Thereof | IRM LLC | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220013735-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OXA1L, ICOSLG, ODC1 | PARP1 1456/4885HTR1A 3920/4885ADRA1D 742/4885 |
| US-20110053932-A1 | Protein Kinase Inhibitors and Methods for Using Thereof | BMX, FRK, FYN | PARP1 2928/4885HTR1A 2702/4885ADRA1D 2707/4885 |
| US-20220089637-A1 | STEROID COMPOUND, AND USE THEREOF AND PREPARATION METHOD THEREFOR | CYP11B1, CYP4A11, CYP11B2 | PARP1 4434/4885HTR1A 1317/4885ADRA1D 1628/4885 |
| US-20140350024-A1 | ANTIMICROBIAL AGENTS | XDH, CXCL8, TLR8 | PARP1 2454/4885HTR1A 4624/4885ADRA1D 2491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.