Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 16/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | NPY1R | P25929 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | NPY2R | P49146 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | THPO | P40225 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8332497 | 1.00 | ADK (1.00) | ADKLMNASLC29A1ALDH1A1GLA | |
| SCHEMBL8321598 | 0.91 | ADK (0.84) | ADKLMNASLC29A1ALDH1A1GLA | |
| SCHEMBL8332893 | 0.88 | ADK (1.00) | ADKLMNAALDH1A1GLAPMP22 | |
| SCHEMBL8975073 | 0.86 | ADK (1.00) | ADK | |
| SCHEMBL17800832 | 0.84 | ADK (1.00) | ADKSLC29A1 | |
| SCHEMBL31617931 | 0.84 | ADK (1.00) | ADKSLC29A1 | |
| SCHEMBL8524307 | 0.84 | ADK (0.88) | ADKLMNASLC29A1ALDH1A1GLA | |
| SCHEMBL8330336 | 0.83 | ADK (0.89) | ADK | |
| SCHEMBL8331350 | 0.82 | ADK (0.69) | ADKSLC29A1 | |
| SCHEMBL8329018 | 0.82 | ADK (0.88) | ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506347-A | ADENOSINE KINASE INHIBITOR | GENSIA, INC. (US) | 1996-04-09 | — | — | US | disclosed |