Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.71 |
| ▸ | MPC2 | O95563 | 2/20 | 0.65 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.60 |
| ▸ | PPARA | Q07869 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | RXRA | P19793 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8282053 | 0.87 | PPARG (0.70) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| Butane SCHEMBL14855731 | 0.86 | PPARG (0.69) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL487116 | 0.85 | PPARG (0.75) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL2608677 | 0.85 | PPARG (0.67) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL19217579 | 0.85 | PPARG (0.67) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL19828508 | 0.85 | PPARG (0.67) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL1131336 | 0.85 | PPARG (0.68) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL1130999 | 0.85 | PPARG (0.67) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL1592234 | 0.84 | PPARG (0.70) | PPARGMPC2CYP2C8CYP2C9FFAR1 | |
| SCHEMBL14188614 | 0.84 | PPARG (0.67) | PPARGMPC2CYP2C8CYP2C9FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578620-A | TREATMENT OF DIABETES AND HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0678511-A2 | Thiazolidine and oxazolidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1995-10-25 | — | — | EP | disclosed |