Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.70 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.63 |
| ▸ | PPARA | Q07869 | 2/20 | 0.63 |
| ▸ | MPC2 | O95563 | 2/20 | 0.61 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487116 | 0.88 | PPARG (0.75) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL8282053 | 0.86 | PPARG (0.70) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL9570670 | 0.84 | FFAR1 (0.71) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL1130999 | 0.84 | PPARG (0.67) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL8975173 | 0.84 | PPARG (0.71) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| Butane SCHEMBL14855731 | 0.83 | PPARG (0.69) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL9570560 | 0.83 | FFAR1 (0.69) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL9570574 | 0.83 | FFAR1 (0.69) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL8957444 | 0.83 | FFAR1 (0.69) | PPARGFFAR1PPARAMPC2CYP2C8 | |
| SCHEMBL9570853 | 0.83 | FFAR1 (0.69) | PPARGFFAR1PPARAMPC2CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092555-A1 | Thiazolidinedione compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-21 | — | — | US | claimed |
| EP-2226321-A2 | Process for producing thiazolidinediones and intermediates thereof | Daiichi Sankyo Company, Limited (JP) | 2010-09-08 | — | — | EP | claimed |
| US-20080103185-A1 | Process for Producing Thiazolidinedione Compound and Production Intermediate Thereof | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-05-01 | — | — | US | claimed |
| EP-1894929-A1 | PROCESS FOR PRODUCING THIAZOLIDINEDIONE COMPOUND AND PRODUCTION INTERMEDIATE THEREOF | Daiichi Sankyo Company, Limited (JP) | 2008-03-05 | — | — | EP | claimed |
| US-20110092555-A1 | Thiazolidinedione compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-04-21 | — | — | US | disclosed |
| EP-2226321-A2 | Process for producing thiazolidinediones and intermediates thereof | Daiichi Sankyo Company, Limited (JP) | 2010-09-08 | — | — | EP | disclosed |
| US-20080103185-A1 | Process for Producing Thiazolidinedione Compound and Production Intermediate Thereof | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-05-01 | — | — | US | disclosed |
| EP-1894929-A1 | PROCESS FOR PRODUCING THIAZOLIDINEDIONE COMPOUND AND PRODUCTION INTERMEDIATE THEREOF | Daiichi Sankyo Company, Limited (JP) | 2008-03-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092555-A1 | Thiazolidinedione compound | GLP1R, DPP4, KCNK4 | PPARG 209/4885FFAR1 2235/4885PPARA 150/4885 |
| US-20080103185-A1 | Process for Producing Thiazolidinedione Compound and Production Intermediate Thereof | INSR, GCKR, GPR119 | PPARG 28/4885FFAR1 92/4885PPARA 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.