Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 19/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328638 | 0.92 | ADK (0.83) | ADKALDH1A1LMNAGLAPMP22 | |
| SCHEMBL8328630 | 0.92 | ADK (0.83) | ADKALDH1A1LMNAGLAPMP22 | |
| SCHEMBL8975594 | 0.91 | ADK (1.00) | ADKALDH1A1LMNAGLAPMP22 | |
| SCHEMBL8975258 | 0.84 | ADK (0.80) | ADK | |
| SCHEMBL8332958 | 0.84 | ADK (0.70) | ADK | |
| SCHEMBL8333506 | 0.83 | ADK (0.84) | ADK | |
| SCHEMBL8333501 | 0.83 | ADK (0.84) | ADK | |
| SCHEMBL8328731 | 0.83 | ADK (1.00) | ADKALDH1A1LMNAGLAPMP22 | |
| SCHEMBL8328727 | 0.83 | ADK (1.00) | ADKALDH1A1LMNAGLAPMP22 | |
| SCHEMBL8975707 | 0.82 | ADK (0.84) | ADKALDH1A1LMNAGLAPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506347-A | ADENOSINE KINASE INHIBITOR | GENSIA, INC. (US) | 1996-04-09 | — | — | US | disclosed |