Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1981047 | 0.85 | CYP3A4 (0.50) | ALDH1A1L3MBTL1 | |
| SCHEMBL21010900 | 0.83 | KEAP1 (0.50) | KEAP1ESR1ESR2ABATTAAR1 | |
| SCHEMBL2945469 | 0.82 | KEAP1 (0.64) | KEAP1ESR1ESR2ABATALOX5 | |
| SCHEMBL398862 | 0.82 | HTR2A (0.48) | ALOX5CYP2C19 | |
| SCHEMBL11131916 | 0.81 | MEN1 (0.40) | TAAR1SLC6A2ALDH1A1IDO1MEN1 | |
| SCHEMBL355039 | 0.81 | HTR2A (0.47) | ALOX5CYP2C19 | |
| SCHEMBL21694307 | 0.81 | KEAP1 (0.68) | KEAP1ESR1ESR2ABATALOX5 | |
| SCHEMBL6280729 | 0.81 | MAPT (0.53) | ALOX5TAAR1SLC6A2KDM4EALDH1A1 | |
| SCHEMBL21010918 | 0.80 | KEAP1 (0.61) | KEAP1ESR1ESR2ABATALOX5 | |
| SCHEMBL5793478 | 0.77 | POLB (0.43) | KDM4EALDH1A1CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457485-B1 | Nonlinear optical devices and methods for making them | AT & T CORP (US) | 1996-04-10 | — | — | EP | disclosed |
| US-5119228-A | Nonlinear optical devices | AT&T BELL LABORATORIES (US) | 1992-06-02 | — | — | US | disclosed |
| EP-0457485-A2 | Nonlinear optical devices and methods for making them | AT&T Corp. (US) | 1991-11-21 | — | — | EP | disclosed |
| US-5045364-A | Nonlinear optical devices and methods | AT&T BELL LABORATORIES (US) | 1991-09-03 | — | — | US | disclosed |