Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131616 | 0.84 | KMT2A (0.47) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL8741548 | 0.77 | KMT2A (0.47) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL5314455 | 0.76 | KMT2A (0.44) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL6131605 | 0.75 | CA12 (0.46) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL6131614 | 0.73 | LMNA (0.52) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL6131660 | 0.72 | CA12 (0.48) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL8719474 | 0.71 | KMT2A (0.44) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL8478713 | 0.70 | LMNA (0.51) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL6131569 | 0.70 | LMNA (0.55) | KMT2ALMNATHRBCYP2C19 | |
| SCHEMBL6131546 | 0.70 | KMT2A (0.45) | KMT2ALMNATHRBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506345-A | ANTIHYPOXIC AGENTS | AMERSHAM INTERNATIONAL PLC (GB) | 1996-04-09 | — | — | US | claimed |
| US-5387692-A | A bisamine oxime compound containing a 2-nitroimidazole group | AMERSHAM INTERNATIONAL PLC (GB) | 1995-02-07 | — | — | US | claimed |
| US-5506345-A | ANTIHYPOXIC AGENTS | AMERSHAM INTERNATIONAL PLC (GB) | 1996-04-09 | — | — | US | disclosed |
| US-5387692-A | A bisamine oxime compound containing a 2-nitroimidazole group | AMERSHAM INTERNATIONAL PLC (GB) | 1995-02-07 | — | — | US | disclosed |