Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772914 | 0.82 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL7777574 | 0.82 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL7779596 | 0.81 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL216401 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7780733 | 0.78 | PTGS2 (0.83) | PTGS2PTGS1 | |
| SCHEMBL7777863 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7780781 | 0.78 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL7780147 | 0.73 | PTGS2 (0.83) | PTGS2PTGS1 | |
| SCHEMBL7772990 | 0.73 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL7779255 | 0.73 | PTGS2 (0.60) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486534-A | 3,4-substituted pyrazoles for the treatment of inflammation | G. D. SEARLE & CO. (US) | 1996-01-23 | — | — | US | disclosed |