Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SI | P14410 | 2/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2651947 | 0.88 | ALDH1A1 (0.33) | ALDH1A1TDP1LMNAHSD17B10MGAM | |
| SCHEMBL30534800 | 0.80 | KDM4E (0.35) | ALDH1A1TDP1LMNAHSD17B10MGAM | |
| SCHEMBL30534815 | 0.80 | KDM4E (0.35) | ALDH1A1TDP1LMNAHSD17B10MGAM | |
| SCHEMBL5634001 | 0.79 | HMGCR (0.42) | ALDH1A1TDP1LMNAHSD17B10TSHR | |
| SCHEMBL10624961 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TDP1LMNAHSD17B10TSHR | |
| SCHEMBL28339328 | 0.77 | ALDH1A1 (0.36) | ALDH1A1TDP1LMNAHSD17B10TSHR | |
| SCHEMBL407625 | 0.75 | GAA (0.50) | ALDH1A1LMNAHSD17B10MGAMGAA | |
| SCHEMBL2651738 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TDP1LMNAHSD17B10 | |
| SCHEMBL10740178 | 0.72 | MGAM (0.39) | ALDH1A1TDP1TSHRMGAMGAA | |
| SCHEMBL4096745 | 0.71 | ALDH1A1 (0.32) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5506347-A | ADENOSINE KINASE INHIBITOR | GENSIA, INC. (US) | 1996-04-09 | — | — | US | disclosed |