SCHEMBL8975394

SCHEMBL8975394

C=CC(=O)NC(O)(NC(=O)C=C)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
TSHR P16473 2/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
LMNA P02545 1/20 0.36
TGM2 P21980 3/20 0.35
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3136079 0.76 ALDH1A1 (0.44) ALDH1A1CYP2C19CYP3A4CYP2C9TSHR
SCHEMBL11121753 0.76 CYP2C19 (0.41) ALDH1A1CYP2C19CYP3A4CYP2C9TSHR
SCHEMBL27961654 0.76 ALDH1A1 (0.43) ALDH1A1CYP2C19CYP3A4CYP2C9TSHR
SCHEMBL976113 0.76
SCHEMBL2592477 0.75 ALDH1A1 (0.40) ALDH1A1CYP2C19CYP3A4CYP2C9TSHR
SCHEMBL1420537 0.73 ALDH1A1 (0.46) ALDH1A1CYP2C19CYP3A4CYP2C9TSHR
SCHEMBL28473797 0.73 ALDH1A1 (0.46) ALDH1A1CYP2C19CYP3A4CYP2C9TSHR
SCHEMBL5138580 0.72 ALDH1A1 (0.40) ALDH1A1CYP2C19CYP3A4CYP2C9TSHR
SCHEMBL2943903 0.72
SCHEMBL1548739 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1637561-B1 Gloss reducing polymer composition ROHM & HAAS (US) 2014-02-26 EP claimed
EP-0435635-B1 Electrically conductive layer for electrical devices XEROX CORP (US) 1996-09-18 EP claimed
EP-0435633-B1 Electrically conductive layer for electrical devices XEROX CORP (US) 1996-09-11 EP claimed
EP-0264903-B1 Rubbery acrylic polymer, latex and preparation thereof GOODRICH CO B F (US) 1996-04-10 EP claimed
EP-0435634-B1 Conductive and blocking layers for electrophotographic imaging members XEROX CORP (US) 1995-11-02 EP claimed
EP-0224736-B1 Curable compositions AMERICAN CYANAMID CO (US) 1994-04-06 EP claimed
EP-0374182-B1 BIOSPECIFIC POLYMERS KANEGAFUCHI CHEMICAL IND (JP) 1993-11-03 EP claimed
EP-0049910-B1 COPOLYMERS FORMED FROM ACTIVATED ESTER MONOMERS, AND COATING COMPOSITIONS CONTAINING SAID COPOLYMERS AMERICAN CYANAMID COMPANY (US) 1986-02-19 EP claimed