SCHEMBL8975803

SCHEMBL8975803

N=C(N)NCCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.68

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 16/20 0.68
NPY1R P25929 10/20 0.68
NPY5R Q15761 9/20 0.68
NPY2R P49146 6/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29641098 1.00 NPY4R (0.68) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641056 1.00 NPY4R (0.68) NPY4RNPY1RNPY5RNPY2R
SCHEMBL8975655 0.97 NPY4R (0.67) NPY4RNPY1RNPY5RNPY2R
SCHEMBL8975469 0.96 NPY4R (0.73) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29483774 0.96 NPY4R (0.73) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29461992 0.96 NPY4R (0.63) NPY4RNPY1RNPY5RNPY2R
SCHEMBL22133073 0.95 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641130 0.95 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641040 0.95 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29641095 0.95 NPY4R (0.61) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220372172-A1 METHOD AND CARRIER COMPLEXES FOR DELIVERING MOLECULES TO CELLS CORNELL RESEARCH FOUNDATION, INC. (US) 2022-11-24 US claimed
EP-4711005-A2 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH Stealth BioTherapeutics Inc. (US) 2026-03-18 EP disclosed
US-20260061023-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF BARTH SYNDROME STEALTH BIOTHERAPEUTICS INC. (US) 2026-03-05 US disclosed
US-20260062752-A1 METHODS AND COMPOSITIONS FOR DETECTING AND DIAGNOSING DISEASES AND CONDITIONS STEALTH BIOTHERAPEUTICS INC. (US) 2026-03-05 US disclosed
US-12527770-B2 Methods of managing pain using dexmedetomidine transdermal delivery devices TEIKOKU PHARMA USA, INC. (US) 2026-01-20 US disclosed
US-20250319152-A1 METHODS FOR THE PREVENTION OR TREATMENT OF LEFT VENTRICLE REMODELING STEALTH BIOTHERAPEUTICS INC. (US) 2025-10-16 US disclosed
US-20250276116-A1 METHODS OF MITIGATING MYOCARDIAL DAMAGE DUE TO EXTRACORPOREAL MEMBRANE OXYGENATION TUFTS MEDICAL CENTER, INC. 2025-09-04 US disclosed
US-20250263433-A1 METHODS FOR REDUCING CD36 EXPRESSION CORNELL RESEARCH FOUNDATION, INC. (US) 2025-08-21 US disclosed
US-20250262269-A1 METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE STEALTH BIOTHERAPEUTICS INC. (US) 2025-08-21 US disclosed
US-20250255929-A1 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH STEALTH BIOTHERAPEUTICS INC. (US) 2025-08-14 US disclosed
EP-3698832-B1 METHODS AND DEVICES FOR SMOKING URGE RELIEF FONTEM HOLDINGS 1 BV (NL) 2022-07-13 EP disclosed
US-11376304-B2 Methods and compositions for the prevention and treatment of disease STEALTH BIOTHERAPEUTICS INC. (US) 2022-07-05 US disclosed
US-11366104-B2 Methods of identifying and monitoring mitochondrial dysfunction using monocyte screening STEALTH BIOTHERAPEUTICS INC. (US) 2022-06-21 US disclosed
EP-4005582-A1 TREATMENT OF LEFT VENTRICULAR REMODELING Stealth BioTherapeutics Inc. (US) 2022-06-01 EP disclosed
EP-4000690-A1 COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF MITOCHONDRIAL MYOPATHIES Stealth BioTherapeutics Inc. (US) 2022-05-25 EP disclosed
US-11312993-B2 Methods and compositions for detecting and diagnosing diseases and conditions STEALTH BIOTHERAPEUTICS INC. (US) 2022-04-26 US disclosed
US-11266709-B2 Methods for the regulation of matrix metalloproteinase expression STEALTH BIOTHERAPEUTICS INC. (US) 2022-03-08 US disclosed
EP-0350221-B1 Dermorphin analogs, their methods of preparation, pharmaceutical compositions, and methods of therapeutic treatment using the same ASTRA AB (SE) 1996-04-17 EP disclosed
US-5312899-A Dermorphin analogs BIOCHEM PHARMA, INC. (CA) 1994-05-17 US disclosed
EP-0350221-A2 Dermorphin analogs, their methods of preparation, pharmaceutical compositions, and methods of therapeutic treatment using the same Astra Aktiebolag (SE) 1990-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260061023-A1 METHODS AND COMPOSITIONS FOR THE PREVENTION OR TREATMENT OF BARTH SYNDROME ARG2, ARGLU1, BCAT1 NPY4R 2600/4885NPY1R 872/4885NPY5R 1341/4885
US-20250255929-A1 METHODS FOR REDUCING RISKS ASSOCIATED WITH HEART FAILURE AND FACTORS ASSOCIATED THEREWITH TNNI3, TNNT2, FABP3 NPY4R 2454/4885NPY1R 1553/4885NPY5R 2704/4885
US-12527770-B2 Methods of managing pain using dexmedetomidine transdermal delivery devices OPRD1, OPRK1, OPRM1 NPY4R 448/4885NPY1R 252/4885NPY5R 244/4885
US-20250319152-A1 METHODS FOR THE PREVENTION OR TREATMENT OF LEFT VENTRICLE REMODELING ARG2, TNNT2, MYLK2 NPY4R 700/4885NPY1R 913/4885NPY5R 680/4885
US-20260062752-A1 METHODS AND COMPOSITIONS FOR DETECTING AND DIAGNOSING DISEASES AND CONDITIONS ARG2, MTPN, TNNT2 NPY4R 3734/4885NPY1R 3368/4885NPY5R 3526/4885
US-11376304-B2 Methods and compositions for the prevention and treatment of disease COL2A1, ALPI, COL14A1 NPY4R 223/4885NPY1R 735/4885NPY5R 484/4885
US-20250262269-A1 METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE RNPEP, TNNI3, BDKRB1 NPY4R 350/4885NPY1R 209/4885NPY5R 173/4885
US-20250276116-A1 METHODS OF MITIGATING MYOCARDIAL DAMAGE DUE TO EXTRACORPOREAL MEMBRANE OXYGENATION TNNI3, TNNT2, MB NPY4R 4783/4885NPY1R 4818/4885NPY5R 4367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.