SCHEMBL8975577

SCHEMBL8975577

C(CCOCC1CO1)COCC1CO1.CCCC(O)O

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.66
TDP1 Q9NUW8 1/20 0.66
SMN1; SMN2 Q16637 1/20 0.65
TSHR P16473 2/20 0.62
MAPK1 P28482 1/20 0.39
PDK1 Q15118 1/20 0.39
SPHK2 Q9NRA0 2/20 0.34
SPHK1 Q9NYA1 1/20 0.34
USP2 O75604 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7136106 0.98 ALDH1A1 (0.64) ALDH1A1TDP1SMN1; SMN2TSHRMAPK1
SCHEMBL28280957 0.95 ALDH1A1 (0.75) ALDH1A1TDP1SMN1; SMN2TSHRPDK1
SCHEMBL28240724 0.91 SMN1; SMN2 (0.56) ALDH1A1TDP1SMN1; SMN2TSHRMAPK1
SCHEMBL18110 0.89 SMN1; SMN2 (0.52) ALDH1A1TDP1SMN1; SMN2TSHRMAPK1
Methylamine SCHEMBL28321012 0.86 SMN1; SMN2 (0.48) ALDH1A1TDP1SMN1; SMN2TSHRMAPK1
Water SCHEMBL29133266 0.86 SMN1; SMN2 (0.48) ALDH1A1TDP1SMN1; SMN2TSHRMAPK1
1,4-Butanediol SCHEMBL8975571 0.85 SMN1; SMN2 (0.49) ALDH1A1TDP1SMN1; SMN2TSHRMAPK1
SCHEMBL28044375 0.84 SMN1; SMN2 (0.47) ALDH1A1TDP1SMN1; SMN2TSHRMAPK1
SCHEMBL20595266 0.82 ALDH1A1 (0.60) ALDH1A1TDP1SMN1; SMN2TSHRMAPK1
SCHEMBL8459408 0.82 ALDH1A1 (0.75) ALDH1A1TDP1SMN1; SMN2TSHRSPHK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5525645-A Resin composition for optical molding ASAHI DENKA KOGYO K.K. (JP) 1996-06-11 US disclosed