Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.94 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11636520 | 0.97 | RAB9A (1.00) | RAB9ASLC6A2SLC6A3TP53CYP1A2 | |
| SCHEMBL8975590 | 0.92 | RAB9A (0.80) | RAB9ASLC6A2SLC6A3TP53CYP1A2 | |
| Palmitic Acid SCHEMBL11482483 | 0.84 | RAB9A (0.72) | RAB9ASLC6A2SLC6A3TP53CYP1A2 | |
| SCHEMBL127216 | 0.81 | RAB9A (0.64) | RAB9ATP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4877646 | 0.81 | TP53 (0.84) | RAB9ASLC6A2SLC6A3TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL11484449 | 0.81 | RAB9A (0.71) | RAB9ATP53CYP1A2CYP3A4CYP2D6 | |
| Pamoic Acid SCHEMBL11489611 | 0.79 | RAB9A (0.64) | RAB9ASLC6A2SLC6A3CYP3A4MEN1 | |
| SCHEMBL20490270 | 0.78 | RAB9A (0.59) | RAB9ASLC6A2SLC6A3TP53CYP1A2 | |
| SCHEMBL4502913 | 0.77 | CYP1A2 (0.73) | CYP1A2CYP2D6MEN1POLBKMT2A | |
| SCHEMBL14273942 | 0.77 | OPRL1 (0.65) | RAB9ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475844-B1 | Use of N-(1.hexahydroazepinylalkyl) acetamides for the manufacture of medicaments for the treatment of disorders of the cholineogic transmission | UNIV CAEN (FR) | 1996-04-17 | — | — | EP | claimed |
| US-5200405-A | USE OF N-(1-HEXAHYDROAZEPINYLALKYL) ACETAMIDES FOR THE TREATMENT OF CHOLINERGIC TRANSMISSION DISORDERS | ADIR ET COMPAGNIE (FR) | 1993-04-06 | — | — | US | claimed |
| EP-0475844-A1 | Use of N-(1.hexahydroazepinylalkyl) acetamides for the manufacture of medicaments for the treatment of disorders of the cholineogic transmission | UNIVERSITE DE CAEN (FR) | 1992-03-18 | — | — | EP | claimed |
| EP-0475844-B1 | Use of N-(1.hexahydroazepinylalkyl) acetamides for the manufacture of medicaments for the treatment of disorders of the cholineogic transmission | UNIV CAEN (FR) | 1996-04-17 | — | — | EP | disclosed |
| US-5200405-A | USE OF N-(1-HEXAHYDROAZEPINYLALKYL) ACETAMIDES FOR THE TREATMENT OF CHOLINERGIC TRANSMISSION DISORDERS | ADIR ET COMPAGNIE (FR) | 1993-04-06 | — | — | US | disclosed |
| EP-0475844-A1 | Use of N-(1.hexahydroazepinylalkyl) acetamides for the manufacture of medicaments for the treatment of disorders of the cholineogic transmission | UNIVERSITE DE CAEN (FR) | 1992-03-18 | — | — | EP | disclosed |