Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 2/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.54 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 3/20 | 0.51 |
| ▸ | SNCA | P37840 | 3/20 | 0.51 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5905844 | 0.91 | ALDH1A1 (0.60) | MAPTALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL5905842 | 0.91 | ALDH1A1 (0.60) | MAPTALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL1498298 | 0.83 | MAPT (0.79) | MAPTALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL13409434 | 0.80 | ALDH1A1 (0.55) | MAPTALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL4389193 | 0.79 | ALDH1A1 (0.74) | MAPTALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL5077672 | 0.79 | ALDH1A1 (0.74) | MAPTALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL8571918 | 0.79 | MAPT (0.52) | MAPTALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL8596761 | 0.79 | MAPT (0.52) | MAPTALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL13252668 | 0.78 | MAPT (0.75) | MAPTALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL1717617 | 0.78 | ALDH1A1 (0.50) | MAPTALDH1A1SMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536504-A | Ultramicroemulsions from spontaneously dispersible concentrates containing xanthophyll esters and having antitumor activity | MARIGEN S.A. (CH) | 1996-07-16 | — | — | US | disclosed |