SCHEMBL8975632

SCHEMBL8975632

CNCCC(=O)SCCN

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 4/20 0.33
MAPT P10636 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP1A2 P05177 2/20 0.33
TSHR P16473 2/20 0.33
NOS1 P29475 1/20 0.33
CYP2C19 P33261 1/20 0.33
LMNA P02545 3/20 0.32
CYP3A4 P08684 1/20 0.32
APEX1 P27695 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GABRR3 A8MPY1 1/20 0.30
GABRP O00591 1/20 0.30
GABRD O14764 1/20 0.30
HDAC3 O15379 1/20 0.30
GABBR2 O75899 1/20 0.30
THRB P10828 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB1 P18505 1/20 0.30
GABRG2 P18507 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8975604 0.88 KDM4A (0.34) PAOXMAPTTDP1CYP1A2TSHR
Hydrochloric Acid SCHEMBL8975853 0.88 CYP1A2 (0.38) PAOXCYP1A2TSHRCYP2C19LMNA
Hydrochloric Acid SCHEMBL8975858 0.85 PAOX (0.40) PAOXCYP1A2CYP2C19LMNATHRB
SCHEMBL17164988 0.79 CYP1A2 (0.43) PAOXMAPTTDP1CYP1A2TSHR
Hydrochloric Acid SCHEMBL9128502 0.75 IDO1 (0.42) PAOXMAPTTDP1CYP1A2TSHR
SCHEMBL17633868 0.74 CES1 (0.44) MAPTTDP1CYP1A2TSHRNOS1
Hydrochloric Acid SCHEMBL8975309 0.73 PAOX (0.37) PAOXMAPTCYP1A2TSHRCYP2C19
Hydrochloric Acid SCHEMBL9509927 0.73 CYP1A2 (0.46) PAOXMAPTTDP1CYP1A2TSHR
SCHEMBL19692564 0.72 CES2 (0.46) TDP1TSHRSMN1; SMN2KMT2AHDAC11
SCHEMBL31087278 0.71 TSHR (0.48) PAOXMAPTTDP1CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514282-B1 Alkylamino mercaptoalkylamides or salts thereof acceptable for cosmetic use, their use as a reducing agent and a process for the permanent deformation of hair OREAL (FR) 1996-04-10 EP claimed