SCHEMBL8975664

SCHEMBL8975664

CCCCCC1(C2(CCCC)CCC2)CCCC1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CETP P11597 3/20 0.33
TSHR P16473 1/20 0.33
THRB P10828 1/20 0.33
SIRT2 Q8IXJ6 1/20 0.33
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9797548 0.92 TSHR (0.35) CETPTSHRTHRBSIRT2CNR1
SCHEMBL29123260 0.90 TSHR (0.40) CETPTSHRTHRBSIRT2CNR1
SCHEMBL2429504 0.90 CETP (0.33) CETPTSHRTHRB
SCHEMBL29021915 0.87 LMNA (0.30) TSHR
SCHEMBL6760472 0.85
SCHEMBL4177406 0.83 CETP (0.31) CETP
SCHEMBL16509475 0.81 CETP (0.35) CETPTSHRTHRBSIRT2CNR1
SCHEMBL1534358 0.79 CETP (0.32) CETPCNR1CNR2
SCHEMBL5678679 0.78 CNR1 (0.35) CETPSIRT2CNR1CNR2
SCHEMBL27704183 0.78 CETP (0.35) CETPTSHRTHRBSIRT2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5523333-A FORMING POLYURETHANE BY HOMOGENIZING, DISSOLVING HYDROCARBON BLOWING AGENT IN POLYETHER FIRST BASF CORPORATION (US) 1996-06-04 US disclosed
US-5523332-A POLYISOCYANATE DISPERSIONS WITH BLOWING AGENT AND POLYESTER SOLUTIONS ALSO CONTAINING BLOWING AGENT AND COMPATIBILIZER, TO BE MIXED FOR FOAMS BASF CORPORATION (US) 1996-06-04 US disclosed
US-5455283-A Polmerizing isocyanate and polyether with hydrofluorocarbon as blowing agent BASF CORPORATION (US) 1995-10-03 US disclosed